ISSAKS 2017

Malcolm Maden

Malcolm Maden

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Malcolm Maden

Professor Malcolm Maden is a member of the Department of Biology at the University of Florida in Gainesville, Florida, USA and a Joint Professor in the Department of Molecular Geentics and Microbiology.  He received his PhD in Genetics from the University of Birmingham in 1975 on the subject of Urodele limb regeneration.  He did a post-docrotal fellowship at the University of Sussex and then was a sceintist at the National Insitute for Medical Research, London for 11 years where his studies centered on the role of retinoic acid in development and regeneration of several different vertebrate systems including limb regeneration, the developing central nervous system and the developing limb.  In 1998 he moved to King’s College London to teach Antomy and continue his research on retinoic acid where this work became more translational and concerned the potential roles for retinoic acid in the treatment of neurological and pulmonary diseases.  In particular retinoic acid became a potential treatment for emphysema and his work on the nervous system revealed that retinoic acid was a lead compound for the treatment of Alzheimer’s disease. In 2008 he moved to the University of Florida and returned to study the regeneration of various systems in Urodeles and mammals.  His work is currently centered on the role of retinoic acid in limb regeneration and nervous system regeneration in Urodeles and the possibilities of regeneration existing in mammals.  The latter work has been stimulated by the discovery that the skin of the spiny mouse can regenerate hair, dermis and skeletal muscle in a scar-free manner revealing hitherto unsuspected abilities in higher vertebrates. He has published over 190 scientific papers on these subjects, is an associate editor of two journals, the International Journal of Developmental Biology, and Regeneration, is on the scientific advisory board of two companies and is a member of Faculty of 1000.